Burnout is a prevalent and escalating issue in emergency nursing, driven by factors such as increased patient demand, overcrowding, staffing shortages, workplace violence and critical incident exposure. This article explores the systemic, environmental and psychological causes of burnout, and examines its detrimental effects on nurses’ well-being and patient safety. Strategies for identifying, managing and preventing burnout are discussed, including recognising early symptoms, managing the emotional effect of trauma, supporting personal resilience and the importance of organisational measures such as improved staffing, leadership support and workplace safety initiatives. Practical interventions to develop resilience, enhance emotional regulation and mitigate the effect of shiftwork are explored. The article emphasises that while individual strategies are valuable, systemic changes are essential to address the root causes of burnout. By implementing multilevel approaches, emergency nurses and healthcare organisations can protect staff well-being and sustain the delivery of safe, high-quality care.