Anaphylaxis is becoming more common, and research shows that effective patient education can reduce subsequent events. There is, therefore, a growing need to train patients with confirmed anaphylaxis to avoid triggers, recognise symptoms and become confident in administering adrenaline in an emergency. As adrenaline auto-injectors are replaced in primary care, practice nurses can play an important role in educating and updating patients in anaphylaxis prevention and treatment. A best practice parameter is proposed for the key elements of training for patients with confirmed anaphylaxis requiring adrenaline treatment.